On September 14, 2024, the board of directors of Minerva Neurosciences, Inc. (the "Company") set the expected date for the Company's 2024 annual meeting of stockholders (the "Annual Meeting") for December 5, 2024, which is more than 30 days before or after the one-yearanniversary of the Company's 2023 annual meeting of stockholders. In light of the foregoing, and in accordance with the Company's amended and restated bylaws (the "Bylaws"), in order for any business to be brought before the Annual Meeting by a stockholder and for any person to be nominated for election to the Company's board of directors at the Annual Meeting by a stockholder, such stockholder must notify the Company of such intention by notice received at the Company's principal executive offices not later than the close of business on October 1, 2024. Stockholder proposals intended for inclusion in the Company's proxy statement for the Annual Meeting pursuant to Rule 14a-8under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), must be received at the Company's principal executive offices no later than the close of business on October 1, 2024, which the Company believes is a reasonable time before it begins to print and mail proxy materials for the Annual Meeting. In addition, all such stockholder notices and stockholder proposals must conform to the applicable requirements of the Bylaws, the rules and regulations promulgated under the Exchange Act and other applicable law. All such notices and stockholder proposals are to be directed to: Minerva Neurosciences, Inc., Attention: Secretary, 1500 District Avenue, Burlington, Massachusetts 01803.