Management Change/Compensation Form 8 K

Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On August 1, 2024, Dr. Susan Altschuller notified Mural Oncology plc (the "Company") of her decision to resign as a member of the Board of Directors of the Company (the "Board") and all committees of the Board on which she serves, effective as of September 1, 2024. Dr. Altschuller informed the Company that her resignation was not related to any disagreement with the Company on any matter relating to its operations, policies or practices.