Material Event Form 8 K

On September 9, 2024, Illumina, Inc. (the "Company") repaid in full all indebtedness and other obligations outstanding under, and terminated, the 364-daydelayed draw credit agreement (the "Credit Agreement") among the Company, as the borrower, the lenders from time to time party thereto and JPMorgan Chase Bank, N.A., as administrative agent (in such capacity, the "Administrative Agent"). The Company's payment under the Credit Agreement was $761 million. The Company did not incur any prepayment premium or penalty (other than customary breakage costs). Reference is hereby made to the Company's Current Report on Form 8-Kfiled on June 17, 2024, for a description of the terms of the Credit Agreement.