Management Change/Compensation Form 8 K

Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Effective October 7, 2024 (the "Appointment Date"), the Board of Nuvation Bio Inc. (the "Company") appointed Philippe Sauvage as the Company's Chief Financial Officer and Principal Financial Officer.

Prior to joining the Company, Mr. Sauvage, 47 years old, served as Senior Vice President, Global Head of Operations and Access for Sanofi from 2020 to 2024. Mr. Sauvage also served Sanofi as Head of Commercial Strategy and Portfolio Marketing - DUPIXENT from 2019-2020, Chief Financial Officer for Sanofi-Genzymeand Sanofi North America from 2015-2019, and Chief Financial Officer - JPAC region from 2012-2015.

Philippe received a Research Masters degree in Macro-Economics from Panthéon-Sorbonne University and a Master of Science, Engineering degree from École Polytechnique. Mr. Sauvage also completed an elite Civil Servant Education in Corps des Mines at Mines ParisTech.

In connection with the appointment of Mr. Sauvage as Chief Financial Officer, the Compensation Committee of the Board approved the Company's entry into an employment agreement (the "Employment Agreement") with Mr. Sauvage, which includes the following terms: (i) an initial annual base salary of $510,000 per year (the "Initial Base Salary"), (ii) an annual discretionary bonus of up to 45% of the Initial Base Salary and (iii) an option to purchase up to 750,000 shares of the Company's common stock (the "Option Award"), with 1/4th of the shares underlying the Option Award vesting and becoming exercisable on the one-yearanniversary of the Appointment Date and 1/48th of the shares underlying the Option Award vesting and becoming exercisable on a monthly basis thereafter, among other benefits. Additionally, in the event Mr. Sauvage experiences an involuntary termination without cause, he would receive a cash severance in an amount equal to 12 months of base salary, as well as 12 months of COBRA health insurance reimbursement. Upon a termination without cause or a resignation for "good reason" (as defined in the Employment Agreement) within 12 months after a change in control of our company, Mr. Sauvage would be eligible to receive the cash severance and COBRA reimbursement described above, and also (1) a lump sum cash payment equal to 100% of target annual bonus and (2) full acceleration of vesting of any equity awards that are subject to vesting based solely on the passage of time. In connection with his appointment as Chief Financial Officer, Mr. Sauvage has entered into the Company's standard form of indemnification agreement, a copy of which was filed as Exhibit 10.8 to the Company's Registration Statement on Form S-4/A(File No. 333-250036)filed with the Securities and Exchange Commission on January 19, 2021.

No family relationships exist between Mr. Sauvage and any of the Company's directors or other executive officers. There are no arrangements between Mr. Sauvage and any other person pursuant to which he was selected as an officer, nor are there any transactions to which the Company is or was a participant and in which Mr. Sauvage has a material interest subject to disclosure under Item 404(a) of Regulation S-K.