Material Agreement Form 8 K

Item 1.01 Entry into a Material Definitive Agreement.

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On October 8, 2024, Soligenix, Inc. (the "Company") and its subsidiaries, Soligenix UK Limited, Enteron Pharmaceuticals, Inc., Soligenix BioPharma Canada Incorporated, Soligenix NE B.V., and Soligenix Biopharma HI, Inc., as borrowers (collectively referred to as the "Borrower"), entered into an amendment (the "Amendment") to the Loan and Security Agreement (as previously amended, the "Loan Agreement") dated December 15, 2020 with Pontifax Medison Finance (Israel) L.P. and Pontifax Medison Finance (Cayman) L.P. (collectively, the "Lenders") and Pontifax Medison Finance GP, L.P., in its capacity as administrative agent and collateral agent for itself and Lenders. The motivation for entering into the Amendment was to potentially further extend the Company's cash runway by allowing the remaining amounts owed under the loan to be satisfied with stock in lieu of cash.

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The Amendment reduced the conversion price with respect to the remaining principal amount under the Loan Agreement to (a) $3.81 for the first 501,648 shares of the Company's common stock issuable upon conversion following October 7, 2024 and (b) $4.23 with respect to all shares of the Company's common stock issuable in excess of the first 501,648 shares so issued.

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None of the other terms of the Loan Agreement were modified in any material respect.

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The foregoing description of the Amendment does not purport to be complete and is qualified in its entirety by reference to the Amendment, which is attached hereto as Exhibit 10.1 and incorporated herein by reference.

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