Regulation FD Disclosure Form 8 K

On September 26, 2024, Bristol Myers Squibb ("BMS") announced that the U.S. Food and Drug Administration (FDA) approved a New Drug Application (NDA) for KarXT (xanomeline-trospium) for the treatment of schizophrenia in adults. BMS intends to market KarXT as Cobenfy.

As part of the March 2023 royalty agreement with PureTech Health plc ("PureTech"), Royalty Pharma plc ("Royalty Pharma" or the "Company") paid $100 million upfront with up to $400 million in additional payments contingent on the achievement of certain regulatory and commercial milestones in exchange for a 3% royalty on sales up to $2 billion annually, after which threshold Royalty Pharma will receive a 1% royalty. Royalty Pharma will pay PureTech a $25 million milestone as a result of this approval.

Forward-Looking Statements

The information set forth herein does not purport to be complete or to contain all of the information you may desire. Statements contained herein are made as of the date of this Form 8-Kunless stated otherwise, and neither the delivery of this Form 8-Kat any time, nor any sale of securities, shall under any circumstances create an implication that the information contained herein is correct as of any time after such date or that information will be updated or revised to reflect information that subsequently becomes available or changes occurring after the date hereof.

This Form 8-Kcontains statements that constitute "forward-looking statements" as that term is defined in the United States Private Securities Litigation Reform Act of 1995, including statements that express the Company's opinions, expectations, beliefs, plans, objectives, assumptions or projections regarding future events or future results, in contrast with statements that reflect historical facts. Examples include discussion of our strategies, financing plans, growth opportunities and market growth. In some cases, you can identify such forward-looking statements by terminology such as "may," "might," "will," "should," "expects," "plans," "anticipates," "believes," "estimates," "target," "forecast," "guidance," "goal," "predicts," "project," "potential" or "continue," the negative of these terms or similar expressions.

Forward-looking statements are based on management's current beliefs and assumptions and on information currently available to the Company. However, these forward-looking statements are not a guarantee of our performance, and you should not place undue reliance on such statements. Forward-looking statements are subject to many risks, uncertainties and other variable circumstances, and other factors. Such risks and uncertainties may cause the statements to be inaccurate and readers are cautioned not to place undue reliance on such statements. Many of these risks are outside of the Company's control and could cause its actual results to differ materially from those it thought would occur. The forward-looking statements included in this Form 8-Kare made only as of the date hereof. The Company does not undertake, and specifically declines, any obligation to update any such statements or to publicly announce the results of any revisions to any such statements to reflect future events or developments, except as required by law.