Latest-Generation Olympus Endoscopy System Launches in Brazil

SÃO PAULO, Brazil, (September 3, 2024) - Olympus Latin America announced today the Brazilian launch of the EVIS X1™ endoscopy system¹, Olympus' most advanced endoscopy system to-date.

Two events supporting the launch will feature virtual lectures by Dr. Yoji Takeuchi about colorectal cancer and the role Olympus technology can play in the detection and treatment of the disease and hands-on demonstrations of the EVIS X1™ system. The events will be held Sept. 4 in Rio de Janeiro and Curitiba and Sept. 19 in Brasilia.

Dr. Yoji Takeuchi, Department of Gastrointestinal Oncology, Osaka International Cancer Institute, will present the lecture "Prevention of Colorectal Cancer Development Using EVIS X1™." Dr. Takeuchi will examine colorectal cancer (CRC) incidence rates, the effect of colonoscopy on minimizing the risks of CRC and the correlation between adenoma detection rates and CRC deaths. He will also discuss the use in endoscopy of EVIS X1's visualization technologies: Texture and Color Enhancement Imaging (TXI™) technology, Red Dichromatic Imaging (RDI™) technology, Brightness Adjustment Imaging with Maintenance of Contrast (BAI-MAC™) technology and Narrow Band Imaging™ (NBI™) technology.

A study looking at CRC rates in Latin America found that the death rate from CRC grew by 20% in the region between 1990 and 2019, even as mortality rates declined by about 4.3% globally during the same period. While deaths from CRC are forecast to continue dropping in most countries through 2035, researchers do not project a similar decrease in Latin American and Caribbean countries.²

Dr. Gustavo Andrade de Paulo, a gastroenterologist with Hospital Israelita Albert Einstein and a member of the Brazilian Society of Digestive Endoscopy, was the first user of EVIS X1 in Brazil.

"Preventive screenings are so important in the battle against diseases like colorectal cancer, and physicians need the best technologies available to detect, diagnose and treat a variety of gastrointestinal disorders," said Dr. de Paulo. "The visualization technologies available through the EVIS X1™ system provide physicians with a clear and detailed view of the GI tract that can help them perform thorough screenings and guide the best treatment options for our patients."

The EVIS X1™ endoscopy system includes two compatible gastrointestinal endoscopes: the GIF-1100 gastrointestinal videoscope indicated for use within the upper digestive tract and the CF-HQ1100DL/I colonovideoscope indicated for use within the lower digestive tract. The lightweight ErgoGrip control section of these endoscopes is ergonomically designed to provide a comfortable and stable grip and ease in reaching angulation control knobs and scope switches. Features of the EVIS X1 system's visualization technologies include:

• Texture and Color Enhancement Imaging: TXI™ technology is designed to increase the visibility of lesions and polyps by enhancing image color and texture.⁴
• Red Dichromatic Imaging: RDI™ technology is designed to enhance the visibility of deep blood vessels and bleeding points.²
• Brightness Adjustment Imaging with Maintenance of Contrast: BAI-MAC™ technology is designed to correct the brightness levels in dark areas of the endoscopic image, while maintaining the brightness of lighter areas, to increase the total distance view.⁵
• Narrow Band Imaging™: NBI™ technology enhances visual observation of mucosal and vascular patterns by utilizing specific blue and green wavelengths absorbed by hemoglobin.²

TXI™, RDI™, BAI-MAC™ and NBI™ technologies are not intended to replace histopathological sampling as a means of diagnosis. These are adjunctive tools for endoscopic examination that can be used to supplement Olympus white light imaging.

As Olympus works to provide physicians with technology to help treat their patients, the company remains committed to its mission of professional education to ensure that healthcare professionals are fully equipped to use our medical devices safely and effectively. Olympus provides a variety of educational resources through Olympus Continuum, a global educational platform designed to provide the healthcare community with ready access to the latest training and learning opportunities.

"Professional education plays a vital role in integrating new technologies into clinical practice to help ensure they lead to real improvements in patient outcomes," said Dr. John de Csepel, Chief Medical Officer, Olympus Corp. "Medical education is so important as technology and procedures innovate at a rapid pace. We are working to help elevate the standard of patient care by providing the latest technology and innovative learning methods to all of Latin America."

For more information, please visit the EVIS X1™ endoscopy system product page.

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About Olympus Latin America
A leading medical technology company, Olympus uses innovative capabilities in medical technology, therapeutic intervention, and precision manufacturing to help healthcare professionals deliver diagnostic, therapeutic, and minimally invasive procedures to improve clinical outcomes, reduce overall costs, and enhance the quality of life for patients.

The Olympus Latin America Division (LAD) encompasses three subsidiaries within Olympus Corporation of the Americas including Olympus Latin America, Olympus America de México, and Olympus Optical do Brazil. Throughout their respective regions, each subsidiary manages Olympus' operations, distributor partnerships, and workforces in roles such as sales, marketing and support functions. For more information, visit medical.olympuslatinoamerica.com.

¹ ANVISA: 82487469007, 82487469008, 82487469009, 82487469010

² Muzi, Camila D.; Banegas, Matthew P.; Guimarães, Raphael M., "Colorectal cancer disparities in Latin America: Mortality trends 1990-2019 and a paradox association with human development," PLOS ONE, Pub. Aug. 25, 2023

³ Data on file with Olympus (internal testing in 2017)

⁴ Data on file with Olympus (D00489968)

⁵ Data on file with Olympus (DC00436067)

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