Neogen Corporation

10/10/2024 | Press release | Distributed by Public on 10/11/2024 10:59

Best Practices to Prevent Mycotoxin Outbreaks

Preventing mycotoxin outbreaks is critical in the agriculture, food production, and storage industries as it helps ensure the safety and quality of products. Mycotoxins are toxic compounds produced by certain types of molds, which can contaminate crops and subsequently pose health risks to animals and humans. According to the U.S. Food and Drug Administration, the fungi that produce mycotoxins generally grow during crop production and storage. Here are some best practices to minimize the risk of mycotoxin contamination:

Good Agriculture Practices (GAPs)

Start at the source in the field during planting and harvest season. Looking at crop varieties is a foundational aspect of GAP to prevent and minimize mycotoxin contamination. Proper soil preparation, including plowing and tilling, can help reduce the presence of fungal spores on crop residue. Soil should be tested to determine the appropriate levels of nutrients and pH. In addition, implementing efficient irrigation practices can help maintain optimal soil moisture levels to reduce the risk of fungal growth. Pests and weeds are other factors that may contribute to fungal growth. Insects can wound plants or act as paths for fungal spores. Weeds can compete with crops for nutrients and water, weakening plants and making them more susceptible to fungal infections.

When conditions are favorable for fungal growth, the application of fungicides can help prevent infection or mycotoxin production. Fungicides should be applied according to best practices, which include using the correct dosage, timing, and method of application to maximize effectiveness and minimize environmental impact.

Timely, careful harvesting is crucial for reducing mycotoxin contamination. Crops should be harvested at the optimal time of maturity but before they become overly dry or wet, increasing the risk of fungal growth. Delayed harvesting can lead to prolonged exposure to wet conditions, increasing the possibility of fungal infection and mycotoxin production.

Proper Drying and Storage

Proper drying and storage of grains and ingredients plays a vital role in mycotoxin prevention. Grains should be dried to safe moisture levels immediately after harvest to reduce mold growth. Delays in drying can lead to an increase in moisture content, which creates ideal conditions for fungi to grow and produce mycotoxins.

Once dried, the grains must be stored in conditions that prevent any increase in moisture levels. This can be done by using well-ventilated, clean, and dry storage facilities that are designed to keep moisture out. The storage environment should be consistently monitored for temperature and humidity, as changes can cause condensation, which can bring moisture back into the grains. The use of temperature-controlled storage units or silos is ideal, especially in regions with high humidity or varying seasonal temperatures.

To further ensure the safety of stored grains, regular inspections and maintenance of storage facilities are necessary. This includes checking for any signs of mold growth or pest infestations, as both can contribute to increased moisture and fungal contamination. If any compromised grains are detected, they should be removed immediately to prevent the spread of contamination. Additionally, thorough cleaning of storage bins and silos between batches is essential to eliminate any residual mold spores that could infect new stock.

Cleaning and Sanitation

Effective cleaning practices help minimize the presence of mold spores and prevent their spread throughout the production and storage environments. The goal is to maintain high levels of hygiene at every stage of the supply chain, from harvesting equipment to processing facilities and storage units.

1. Equipment Cleaning and Maintenance:

All equipment used in the harvesting, handling, and processing of grains should be cleaned regularly to prevent the buildup of mold spores and mycotoxins. This includes combines, conveyors, augers, and milling machines. After each use, these pieces of equipment should be thoroughly cleaned to remove any residues that could harbor mold spores.

2. Facility Hygiene:

Maintaining a clean processing and storage environment is essential for preventing mycotoxin outbreaks. This starts with routine cleaning of floors, walls, and ceilings to remove dust and debris in storage and processing areas. Mold spores can easily become airborne and spread, so it's important to use cleaning methods that capture and remove spores, rather than displacing them.

3. Sanitation Protocols:

Implementing strict sanitation protocols is key to preventing contamination. Standard operating procedures (SOPs) should be established for cleaning schedules, methods, and approved cleaning agents. These protocols should be tailored to the specific needs of each facility and should consider factors such as the type of grains handled, the climate, and the level of risk for mycotoxin contamination. Workers should be trained in these protocols, including the proper use of personal protective equipment (PPE), to ensure their safety and prevent cross-contamination.

4. Cleaning Between Batches:

Between processing different batches of grains, thorough cleaning is essential to prevent cross-contamination. Residues from previous batches can carry mold spores, which can infect new grains. After cleaning, the equipment should be inspected to ensure that all residues and contaminants have been removed before resuming operation.

Regular Testing and Monitoring

Regular testing and monitoring help with the detection and management of mycotoxin contamination. Routine sampling is the first step in this process; samples should be taken at various stages of the supply chain, including the field, post-harvest, during storage, and throughout processing. Proper sampling techniques, such as composite sampling, ensure that the samples represent the entire batch - providing reliable data for quality control. Rapid screening methods, like enzyme-linked immunosorbent assays (ELISA) and lateral flow tests, are commonly used for on-site detection of mycotoxins. These tests provide quick results, allowing for immediate decision-making regarding the acceptance or rejection of raw materials and finished products. While rapid tests are useful for initial screening, laboratory analysis using high-performance liquid chromatography (HPLC) is necessary for detailed and accurate quantification of mycotoxins. These methods are highly sensitive and provide precise measurements, ensuring compliance with regulatory standards.

Continuous monitoring of storage conditions should also be a high priority, as mentioned previously; high humidity and temperature can promote mold growth. Using sensors and automated monitoring systems to track temperature and humidity in real time helps in maintaining optimal storage conditions and preventing contamination. Keeping detailed records of testing and monitoring activities is vital for traceability and compliance. Documentation should include information on sampling procedures, test methods, results, corrective actions, and follow-up testing. This record-keeping supports audits, investigations, and continuous improvement efforts.

Risk Management Plan

To help ensure contamination is controlled at every stage, a comprehensive mycotoxin risk management plan should be integrated into the overall quality control system. It can help by outlining procedures for regular testing, setting clear roles and responsibilities, and defining response processes. Training programs are also necessary to ensure that staff are prepared to perform sampling and testing correctly. Open communication and collaboration among stakeholders, including farmers, suppliers, processors, and regulatory bodies, enhances the overall approach to mycotoxin management. Sharing information about industry updates, potential risks, testing results, and contamination events, helps ensure that everyone is aligned in their efforts to prevent contamination. Implementing these comprehensive testing and monitoring practices helps the industry manage mycotoxin risks effectively, for the utmost safety and quality of products.

By implementing comprehensive strategies such as good agriculture practices, proper drying and storage, thorough cleaning and sanitation, and regular testing and monitoring, industries can significantly reduce the risk of mycotoxin contamination. These practices create a robust framework for identifying and addressing potential issues before they impact final product and consumer health. Emphasizing collaboration among stakeholders further enhances the effectiveness of these preventive measures. Ultimately, a proactive and integrated approach to mycotoxin management not only protects consumer health but also ensures the integrity and reliability of food and feed supplies, developing trust in the industry.

Learn more about mycotoxin solutions.

References:

Mycotoxin's Infections and Prevention Methods: State of the Art, Scientific Research Publishing (SCIRP).

Assessment of Agricultural Practices for Controlling Fusarium and Mycotoxins Contamination on Maize Grains: Exploratory Study in Maize Farms, National Center for Biotechnology Information.

Methods to reduce mycotoxin exposure, Grain SA.