Director/PDMR Shareholding

20 November 2024 16:00 GMT

Transaction by Person Discharging Managerial Responsibilities

AstraZeneca PLC (the Company) announces that it was notified on 20 November 2024 that Tony Mok, Non-Executive Director, purchased 3,000 of the Company's American Depositary Shares (ADSs) on 19 November 2024, as set out below. Two ADSs are equivalent to one of the Company's ordinary shares of $0.25 each.

PDMR	Position	Nature of the transaction	Quantity	Price
Tony Mok	Non-Executive Director	Purchase of ADSs	3,000	US$63.40

Further details are set out in the attached notification, made in accordance with the requirements of the EU Market Abuse Regulation (since it forms part of UK law pursuant to the European Union (Withdrawal) Act 2018).

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Tony Mok
2	Reason for the notification
a)	Position/status	Non-Executive Director
b)	Initial notification /Amendment	Initial notification
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	AstraZeneca PLC
b)	LEI	PY6ZZQWO2IZFZC3IOL08
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	AstraZeneca PLC American Depositary Shares CUSIP: 046353108
b)	Nature of the transaction	Purchase of AstraZeneca PLC American Depositary Shares
c)	Price(s) and volume(s)	Price(s) Volume(s) USD 63.398167 3,000
d)	Aggregated information - Aggregated volume - Price	Not applicable - single transaction
e)	Date of the transaction	19 November 2024
f)	Place of the transaction	XNAS

AstraZeneca
AstraZeneca (LSE/STO/Nasdaq: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, development, and commercialisation of prescription medicines in Oncology, Rare Diseases, and BioPharmaceuticals, including Cardiovascular, Renal & Metabolism, and Respiratory & Immunology. Based in Cambridge, UK, AstraZeneca's innovative medicines are sold in more than 125 countries and used by millions of patients worldwide. Please visit astrazeneca.com and follow the Company on social media @AstraZeneca

Contacts
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Adrian Kemp
Company Secretary
AstraZeneca PLC

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