Material Agreement Form 8 K

On June 28, 2024, Incyte Corporation (the "Company") and its subsidiary, Incyte Holdings Corporation ("Incyte Holdings"), entered into Amendment No. 2 ("Amendment No. 2") to the Revolving Credit and Guaranty Agreement dated as of August 21, 2021 among the Company, as borrower, Incyte Holdings, as a guarantor, the lenders from time to time party thereto, J.P. Morgan Chase Bank, N.A. as administrative agent, and the other financial institutions party thereto (such Revolving Credit and Guaranty Agreement, as amended by Amendment No. 1 thereto, the "Existing Credit Agreement" and, as amended by Amendment No. 2, the "Amended Credit Agreement").

Amendment No. 2 extended the maturity date of the revolving credit facility under the Existing Credit Agreement from August 18, 2024 to June 28, 2027.

A copy of Amendment No. 2, which will include a full copy of the Amended Credit Agreement, will be filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the quarter ended June 30, 2024.