Management Change/Compensation Form 8 K

Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On September 17, 2024, Daniel N. Swisher Jr., a member of the Board of Directors (the "Board") of Protagonist Therapeutics, Inc. (the "Company") and a member of the Audit Committee of the Board, resigned from the Board, effective September 17, 2024. Mr. Swisher did not advise the Company of any disagreement with the Company on any matter relating to its operations, policies or practices. Mr. Swisher will continue to serve as an advisor to the Company pursuant to an advisory agreement.

Effective September 19, 2024, Sarah A. O'Dowd, a member of the Board, was appointed to the Audit Committee of the Board, and the size of the Company's Board of Directors was reduced from seven to six.