Students will get their hands dirty in real-world STEM research module

Students participating in the module will collect soil samples from the San Antonio area and analyze soil data to potentially find new antibiotics. Students will then contribute their findings to a global database managed by the Tiny Earth Initiative, an organization that supports student research in pursuit of more effective antibiotics.

"Over 60% of clinically used antibiotics come from soil bacteria, but as soil erodes, so does the opportunity to discover new antibiotics," explained Shields-Menard. "This research addresses the convergence of the soil crisis and the antibiotic resistance crisis. Students will have the opportunity to analyze soil in their own communities to find new antibiotic-producing bacterial isolates."

The U.S. Centers for Disease Control and Prevention describes antimicrobial resistance as "one of the world's most urgent public health problems." It occurs as pathogens develop defense mechanisms against common antibiotic medications. According to the World Health Organization, the process is driven by misuse and overuse of antibiotic drugs. Meanwhile, the development of new, more effective antibiotics has not kept pace with rising resistance levels, meaning that a growing number of bacterial infections are untreatable.

Students in the module will have the opportunity to ask research questions about antibiotic-producing bacteria in soil and find answers by creating and interpreting visualizations from the data that they collect. For example, in the researchers' pilot study, students posed questions such as whether moisture, acidity of soil, traffic density or elevation are linked to the likelihood that soil will produce antibiotics.

The researchers hope that by analyzing their immediate surroundings in a scientific and data-driven manner, and by connecting the process to an urgent, real-world issue, the students taking the module will better understand the practical applications of science and data science.

"By emphasizing relevant and meaningful applications of science, we can improve diverse undergraduate students' motivation and learning in STEM fields," said Thacker.

The module creators also aim to bolster students' understanding of data science, which they say is becoming an increasingly crucial skill in many fields.

"Being data-savvy is not just an advantage but a necessity for college students," said Thacker. "Interacting with and interpreting data enables students to make informed decisions, uncover new insights, and contribute meaningfully to their fields."

This project is slated to run in three microbiology courses at UTSA with approximately 1,000 student participants over the course of a four-year period (2024-2028). The project leads hope that following the initial implementation, the module can be used to enhance STEM classrooms in other universities and schools.