Material Agreement Form 8 K

On August 15, 2024, Sagimet Biosciences Inc. (the "Company") entered into a Controlled Equity Offering^SM Sales Agreement (the "Agreement") with Cantor Fitzgerald & Co. (the "Agent"), pursuant to which the Company from time to time may offer and sell shares (the "ATM Shares") of its Series A common stock, par value $0.0001 per share ("Common Stock"), through or to the Agent (the "ATM Offering"). The ATM Shares will be offered and sold pursuant to a Registration Statement on Form S-3 filed by the Company on August 15, 2024 (the "Registration Statement") and the ATM Offering prospectus that forms a part of such Registration Statement, following such time, if ever, as the Registration Statement is declared effective by the Securities and Exchange Commission. Pursuant to the ATM Offering prospectus, the Company may sell Common Stock having an aggregate offering price of up to $75,000,000.

Subject to the terms and conditions of the Agreement, the Agent will use its commercially reasonable efforts to sell the ATM Shares from time to time, based upon the Company's instructions. The Company has provided the Agent with customary indemnification rights, and the Agent will be entitled to a commission of up to 3.0% of the gross proceeds from each sale of the ATM Shares effectuated through or to the Agent selling the ATM Shares.

Sales of the ATM Shares, if any, under the Agreement may be made in transactions that are deemed to be "at the market offerings" as defined in Rule 415(a)(4) under the Securities Act of 1933, as amended. The Company has no obligation to sell any of the ATM Shares and may at any time suspend offers under the Agreement or terminate the Agreement.

This Form 8-K shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of the ATM Shares in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.

This description of the Agreement does not purport to be complete and is qualified in its entirety by reference to the Agreement, which is attached hereto as Exhibit 10.1 and incorporated by reference herein.