CHARLES RIVER LABORATORIES ANNOUNCES SECOND QUARTER 2024 RESULTS Form 8 K

CHARLES RIVER LABORATORIES ANNOUNCES
SECOND-QUARTER 2024 RESULTS

- Second-Quarter Revenue of $1.03 Billion -

- Second-Quarter GAAP Earnings per Share of $1.74
and Non-GAAP Earnings per Share of $2.80 -

- Board Approves New Stock Repurchase Authorization of $1.0 Billion -

- Revises 2024 Guidance -

WILMINGTON, MA, August 7, 2024 - Charles River Laboratories International, Inc. (NYSE: CRL) today reported its results for the second quarter of 2024. For the quarter, revenue was $1.03 billion, a decrease of 3.2% from $1.06 billion in the second quarter of 2023.

The impact of foreign currency translation reduced reported revenue by 0.3%, a divestiture reduced reported revenue by 0.2%, and an acquisition contributed 0.5% to consolidated second-quarter revenue. Excluding the effect of these items, revenue also declined 3.2% on an organic basis. On a segment basis, organic revenue growth in the Manufacturing Solutions (Manufacturing) segment was more than offset by lower revenue in the Discovery and Safety Assessment (DSA) and Research Models and Services (RMS) segments.

In the second quarter of 2024, the GAAP operating margin decreased to 14.8% from 15.6% in the second quarter of 2023. This GAAP decrease was primarily driven by lower operating margins in the RMS and DSA segments, due in part to costs associated with the Company's restructuring initiatives. On a non-GAAP basis, the second-quarter operating margin increased to 21.3% from 20.4%, driven primarily by lower performance-based compensation accruals, as well as operating margin improvement in the Manufacturing segment.

On a GAAP basis, second-quarter net income attributable to common shareholders was $90.0 million, a decrease of 7.2% from $97.0 million for the same period in 2023. Second-quarter diluted earnings per share on a GAAP basis were $1.74, a decrease of 7.9% from $1.89 for the second quarter of 2023. The GAAP net income and earnings per share decreases were driven primarily by lower revenue and operating income, which included higher costs associated with the Company's restructuring initiatives. On a non-GAAP basis, net income was $144.9 million for the second quarter of 2024, an increase of 4.8% from $138.3 million for the same period in 2023. Second-quarter diluted earnings per share on a non-GAAP basis were $2.80, an increase of 4.1% from $2.69 per share for the second quarter of 2024. The increases in non-GAAP net

income and earnings per share were driven primarily by lower performance-based compensation accruals, as well as higher revenue and operating income in the Manufacturing segment.

James C. Foster, Chair, President and Chief Executive Officer, said, "Our financial performance through the first half of this year has been largely in line with our initial outlook; however, forward-looking DSA trends suggest that demand will not improve during the second half of the year as we had previously anticipated, and in fact, will decline for global biopharmaceutical clients. This has caused us to take a much more negative view of our growth prospects for the second half of the year. We believe that our clients are currently more focused on reassessing their budgets and reprioritizing their pipelines, but continue to view strategic outsourcing as a compelling solution to improve their cost efficiency and speed to market, presenting a longer-term opportunity for us."

"Therefore, it is imperative for us to navigate through this period of softer demand by aggressively managing our cost structure, initiating new and innovative ways to transform our business, being disciplined with our investments, and enhancing our commercial efforts to win new business. We firmly believe that our clients will continue to seek life-saving treatments for rare diseases and other unmet medical needs, which drives us to take further steps to position Charles River for the future. These steps will enable us to emerge as a stronger, leaner partner to help our clients achieve their goals by utilizing our scientific expertise and flexible solutions," Mr. Foster concluded.

Second-Quarter Segment Results

Research Models and Services (RMS)

Revenue for the RMS segment was $206.4 million in the second quarter of 2024, a decrease of 1.7% from $209.9 million in the second quarter of 2023. The Noveprim acquisition in November 2023 contributed 2.7% to second-quarter RMS reported revenue, and the impact of foreign currency translation reduced revenue by 0.5%. Organic revenue decreased by 3.9%, due primarily to lower revenue for non-human primates (NHPs) in China. In addition, lower revenue for research model services and the Cell Solutions business also contributed to the decline. The decline was partially offset by higher sales of small research models, particularly in Europe and China.

In the second quarter of 2024, the RMS segment's GAAP operating margin decreased to 14.5% from 23.3% in the second quarter of 2023. On a non-GAAP basis, the operating margin decreased to 23.1% from 26.4%. The GAAP and non-GAAP operating margin declines were driven primarily by lower NHP revenue. On a GAAP basis, the lower operating margin also reflects higher costs associated with the Company's restructuring initiatives, including site consolidation costs related to the Company's CRADL operations in California.

Discovery and Safety Assessment (DSA)

Revenue for the DSA segment was $627.4 million in the second quarter of 2024, a decrease of 5.4% from $663.5 million in the second quarter of 2023. A divestiture of a small Safety Assessment site reduced reported revenue by 0.3% and the impact of foreign currency translation

reduced DSA revenue by 0.1%. Organic revenue decreased by 5.0%, driven by lower revenue in the Discovery Services and Safety Assessment businesses.

In the second quarter of 2024, the DSA segment's GAAP operating margin decreased to 22.1% from 24.3% in the second quarter of 2023. On a non-GAAP basis, the operating margin decreased to 27.1% from 27.6% in the second quarter of 2023. The GAAP and non-GAAP operating margin decreases were driven primarily by the impact of lower sales volume, partially offset by lower performance-based compensation accruals. On a GAAP basis, the lower operating margin also reflects higher costs associated with the Company's restructuring initiatives, as well as higher acquisition-related adjustments associated with Noveprim.

Manufacturing Solutions (Manufacturing)

Revenue for the Manufacturing segment was $192.3 million in the second quarter of 2024, an increase of 3.1% from $186.5 million in the second quarter of 2023. The impact of foreign currency translation reduced Manufacturing revenue by 0.6%. Organic revenue growth of 3.7% reflected higher revenue across all of the segment's businesses.

In the second quarter of 2024, the Manufacturing segment's GAAP operating margin increased to 19.4% from 13.1% in the second quarter of 2023, and on a non-GAAP basis, the operating margin increased to 26.6%, from 22.9% in the second quarter of 2023. The GAAP and non-GAAP operating margin increases were driven primarily by improved profitability for each of segment's businesses. On a GAAP basis, lower third-party legal costs related to the Microbial Solutions business and lower acquisition-related adjustments also contributed to the increase.

New Stock Repurchase Authorization

The Company's Board of Directors has approved a new stock repurchase authorization of $1.0 billion. This new authorization replaces a prior stock repurchase authorization of $1.3 billion that had $129.1 million remaining on the plan when it was terminated.

Revises 2024 Guidance

The Company is revising its financial guidance for 2024, which was previously updated on May 9, 2024. The reduced guidance primarily reflects the lack of a recovery in demand from our small and mid-sized biotechnology clients in the second half of the year, as well as softer demand trends from global biopharmaceutical clients whose deterioration has become increasingly evident in the past couple of months. As a result, the Company no longer expects that overall demand trends will improve during the second half of the year. In particular, these trends will have a meaningful impact on the outlook for the DSA segment. The Company is implementing restructuring initiatives that are expected to result in annualized cost savings of over $150 million (inclusive of actions implemented last year through the third quarter of 2024), of which approximately $100 million will be realized in 2024.

The Company's 2024 guidance for revenue growth and earnings per share is as follows:

2024 GUIDANCE	CURRENT	PRIOR
Revenue growth/(decrease), reported	(4.5)% - (2.5)%	1.0% - 4.0%
Impact of divestitures/(acquisitions), net	~(0.5)%	~(0.5)%
(Favorable)/unfavorable impact of foreign exchange	--	~(0.5)%
Revenue growth/(decrease), organic (1)	(5.0)% - (3.0)%	0.0% - 3.0%
GAAP EPS estimate	$5.65 - $5.95	$7.60 - $8.10
Acquisition-related amortization (2)	~$2.75	~$2.50
Acquisition and integration-related adjustments (3)	~$0.20	~$0.10
Costs associated with restructuring actions (4)	~$1.00	~$0.35
Certain venture capital and other strategic investment losses/(gains), net (5)	($0.14)	($0.08)
Incremental dividends related to Noveprim (6)	~$0.25	~$0.25
Other items (7)	~$0.20	~$0.20
Non-GAAP EPS estimate	$9.90 - $10.20	$10.90 - $11.40

Footnotes to Guidance Table:

(1) Organic revenue growth is defined as reported revenue growth adjusted for completed acquisitions and divestitures, as well as foreign currency translation.

(2) These adjustments include amortization related to intangible assets, as well as the purchase accounting step-up on inventory and certain long-term biological assets.

(3) These adjustments are related to the evaluation and integration of acquisitions and divestitures, and primarily include transaction, advisory, certain third-party integration, and related costs; as well as fair value adjustments associated with contingent consideration arrangements.

(4) These adjustments primarily include site consolidation, severance, impairment, and other costs related to the Company's restructuring actions.

(5) Certain venture capital and other strategic investment performance only includes recognized gains or losses on certain investments. The Company does not forecast the future performance of these investments.

(6) This item primarily relates to incremental dividends attributable to Noveprim noncontrolling interest holders who may receive preferential dividends for fiscal year 2024.

(7) These items primarily relate to (i) certain third-party legal costs related to investigations by the U.S. government into the NHP supply chain related to our Safety Assessment business; and (ii) charges associated with U.S. and international tax legislation that necessitated changes to the Company's international financing structure.

Webcast

Charles River has scheduled a live webcast on Wednesday, August 7th, at 9:00 a.m. ET to discuss matters relating to this press release. To participate, please go to ir.criver.com and select the webcast link. You can also find the associated slide presentation and reconciliations of GAAP financial measures to non-GAAP financial measures on the website.

Non-GAAP Reconciliations

The Company reports non-GAAP results in this press release, which exclude often-one-time charges and other items that are outside of normal operations. A reconciliation of GAAP to non-GAAP results is provided in the schedules at the end of this press release.

Use of Non-GAAP Financial Measures

This press release contains non-GAAP financial measures, such as non-GAAP earnings per diluted share, non-GAAP operating income, non-GAAP operating margin, and non-GAAP net income. Non-GAAP financial measures exclude, but are not limited to, the amortization of intangible assets and the purchase accounting step-up adjustment on inventory and certain long term biological assets, and other charges and adjustments related to our acquisitions and divestitures, including incremental dividends attributable to Noveprim noncontrolling interest holders and the gain on our sale of our Avian Vaccine business; expenses associated with evaluating and integrating acquisitions and divestitures, including advisory fees and certain other transaction-related costs, as well as fair value adjustments associated with contingent consideration; charges, gains, and losses attributable to businesses or properties we plan to close, consolidate, or divest; severance and other costs associated with our restructuring initiatives; the write-off of deferred financing costs and fees related to debt financing; investment gains or losses associated with our venture capital and other strategic equity investments; certain legal costs in our Microbial Solutions business related to environmental litigation and in our Safety Assessment business related to U.S. government investigations into the NHP supply chain; tax effect of all of the aforementioned matters; and adjustments related to the recognition of deferred tax assets expected to be utilized as a result of changes to the our international financing structure and the revaluation of deferred tax liabilities as a result of foreign tax legislation. This press release also refers to our revenue on both a GAAP and non-GAAP basis: "organic revenue growth," which we define as reported revenue growth adjusted for foreign currency translation, acquisitions, and divestitures. We exclude these items from the non-GAAP financial measures because they are outside our normal operations. There are limitations in using non-GAAP financial measures, as they are not presented in accordance with generally accepted accounting principles, and may be different than non-GAAP financial measures used by other companies. In particular, we believe that the inclusion of supplementary non-GAAP financial measures in this press release helps investors to gain a meaningful understanding of our core operating results and future prospects without the effect of these often-one-time charges, and is consistent with how management measures and forecasts the Company's performance, especially when comparing such results to prior periods or forecasts. We believe that the financial impact of our acquisitions and divestitures (and in certain cases, the evaluation of such acquisitions and divestitures, whether or not ultimately consummated) is often large relative to our overall financial performance, which can adversely affect the comparability of our results on a period-to-period basis. In addition, certain activities and their underlying associated costs, such as business acquisitions, generally occur periodically but on an unpredictable basis. We calculate non-GAAP integration costs to include third-party integration costs incurred post-acquisition. Presenting revenue on an organic basis allows investors to measure our revenue growth exclusive of acquisitions, divestitures, and foreign currency exchange fluctuations more clearly. Non-GAAP results also allow investors to compare the Company's operations against the financial results of other companies in the industry who similarly provide non-GAAP results. The non-GAAP financial measures included in this press release are not meant to be considered superior to or a substitute for results of operations presented in accordance with GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules and regulations. Reconciliations of the non-GAAP financial measures used in

this press release to the most directly comparable GAAP financial measures are set forth in this press release, and can also be found on the Company's website at ir.criver.com.

Caution Concerning Forward-Looking Statements

This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "expect," "intend," "will," "would," "may," "estimate," "plan," "outlook," and "project," and other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These statements also include statements regarding Charles River's expectations regarding the availability of Cambodia-sourced NHPs; the impact of the investigations by the U.S. government into the Cambodia NHP supply chain, including but not limited to Charles River's ability to cooperate fully with the U.S. government; Charles River's ability to effectively manage any Cambodia NHP supply impact; the projected future financial performance of Charles River and our specific businesses, including our expectations with respect to the impact of NHP supply constraints and our ability to gain market share; earnings per share; operating margin; client demand, particularly the future demand for drug discovery and development products and services, including our expectations for future revenue trends; our expectations with respect to pricing of our products and services; our expectations with respect to future tax rates and the impact of such tax rates on our business; our expectations with respect to the impact of acquisitions and divestitures completed in 2021, 2022, and 2023, including the Noveprim acquisition, on the Company, our service offerings, client perception, strategic relationships, revenue, revenue growth rates, revenue growth drivers, and earnings; the development and performance of our services and products, including our investments in our portfolio; market and industry conditions including the outsourcing of services and identification of spending trends by our clients and funding available to them; ability to gain market share and capitalize on business opportunities; the impact of our restructuring initiatives, including annualized savings; the impact of our stock repurchase authorization; and Charles River's future performance as delineated in our forward-looking guidance, and particularly our expectations with respect to revenue, the impact of foreign exchange, interest rates, enhanced efficiency initiatives. Forward-looking statements are based on Charles River's current expectations and beliefs, and involve a number of risks and uncertainties that are difficult to predict and that could cause actual results to differ materially from those stated or implied by the forward-looking statements. Those risks and uncertainties include, but are not limited to: NHP supply constraints and the investigations by the U.S. Department of Justice, including the impact on our projected future financial performance, the timing of the resumption of Cambodia NHP imports into the U.S., our ability to manage supply impact, and potential study delays in our Safety Assessment business attributable to NHP supply constraints; changes and uncertainties in the global economy and financial markets; the ability to successfully integrate businesses we acquire, including Noveprim; the timing and magnitude of our share repurchases; negative trends in research and development spending, negative trends in the level of outsourced services, or other cost reduction actions by our clients; the ability to convert backlog to revenue; special interest groups; contaminations; industry trends; new displacement technologies; USDA and FDA regulations; changes in law; continued availability of products and supplies; loss of key personnel; interest rate and foreign currency exchange rate fluctuations; changes in tax regulation and laws; changes in generally accepted accounting

principles; disruptions in the global economy caused by geopolitical conflicts; and any changes in business, political, or economic conditions due to the threat of future terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas. A further description of these risks, uncertainties, and other matters can be found in the Risk Factors detailed in Charles River's Annual Report on Form 10-K as filed on February 14, 2024, as well as other filings we make with the Securities and Exchange Commission. Because forward-looking statements involve risks and uncertainties, actual results and events may differ materially from results and events currently expected by Charles River, and Charles River assumes no obligation and expressly disclaims any duty to update information contained in this press release except as required by law.

About Charles River

Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit www.criver.com.

# # #

Investor Contact: Media Contact:

Todd Spencer Amy Cianciaruso

Corporate Vice President, Corporate Vice President,

Investor Relations Chief Communications Officer

781.222.6455 781.222.6168

[email protected]@crl.com

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SCHEDULE 1
CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED)
(in thousands, except for per share data)
Three Months Ended	Six Months Ended
June 29, 2024	July 1, 2023	June 29, 2024	July 1, 2023
Service revenue	$	842,900	$	874,891	$	1,659,762	$	1,732,257
Product revenue	183,217	185,046	377,915	357,053
Total revenue	1,026,117	1,059,937	2,037,677	2,089,310
Costs and expenses:
Cost of services provided (excluding amortization of intangible assets)	577,383	578,099	1,155,547	1,143,576
Cost of products sold (excluding amortization of intangible assets)	95,021	82,861	183,574	169,103
Selling, general and administrative	169,791	199,758	356,082	374,604
Amortization of intangible assets	32,270	34,274	64,845	69,190
Operating income	151,652	164,945	277,629	332,837
Other income (expense):
Interest income	3,010	1,426	5,212	2,232
Interest expense	(32,769)	(35,044)	(67,770)	(69,424)
Other income (expense), net	(2,240)	(2,663)	3,593	(5,940)
Income before income taxes	119,653	128,664	218,664	259,705
Provision for income taxes	25,392	29,221	49,921	56,308
Net income	94,261	99,443	168,743	203,397
Less: Net income attributable to noncontrolling interests	180	2,423	1,702	3,246
Net income available to Charles River Laboratories International, Inc.	$	94,081	$	97,020	$	167,041	$	200,151
Calculation of net income per share attributable to common shareholders of Charles River Laboratories International, Inc.
Net income available to Charles River Laboratories International, Inc.	$	94,081	$	97,020	$	167,041	$	200,151
Less: Adjustment of redeemable noncontrolling interest	301	-	702	-
Less: Incremental dividends attributable to noncontrolling interest holders	3,792	-	9,022	-
Net income available to Charles River Laboratories International, Inc. common shareholders	$	89,988	$	97,020	$	157,317	$	200,151
Earnings per common share
Net income attributable to common shareholders:
Basic	$	1.75	$	1.89	$	3.06	$	3.91
Diluted	$	1.74	$	1.89	$	3.04	$	3.90
Weighted-average number of common shares outstanding:
Basic	51,551	51,216	51,494	51,157
Diluted	51,846	51,467	51,810	51,382

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SCHEDULE 2
CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)
(in thousands, except per share amounts)
June 29, 2024	December 30, 2023
Assets
Current assets:
Cash and cash equivalents	$	179,213	$	276,771
Trade receivables and contract assets, net of allowances for credit losses of $24,951 and $25,722, respectively	762,221	780,375
Inventories	349,111	380,259
Prepaid assets	97,892	87,879
Other current assets	110,836	83,378
Total current assets	1,499,273	1,608,662
Property, plant and equipment, net	1,613,895	1,639,741
Venture capital and strategic equity investments	231,859	243,811
Operating lease right-of-use assets, net	386,147	394,029
Goodwill	3,079,693	3,095,045
Intangible assets, net	800,129	864,051
Deferred tax assets	36,109	40,279
Other assets	301,178	309,383
Total assets	$	7,948,283	$	8,195,001
Liabilities, Redeemable Noncontrolling Interests and Equity
Current liabilities:
Accounts payable	$	133,101	$	168,937
Accrued compensation	176,667	213,290
Deferred revenue	247,177	241,820
Accrued liabilities	192,156	227,825
Other current liabilities	198,418	203,210
Total current liabilities	947,519	1,055,082
Long-term debt, net and finance leases	2,409,380	2,647,147
Operating lease right-of-use liabilities	428,587	419,234
Deferred tax liabilities	165,183	191,349
Other long-term liabilities	224,520	223,191
Total liabilities	4,175,189	4,536,003
Redeemable noncontrolling interest	46,076	56,722
Equity:
Preferred stock, $0.01 par value; 20,000 shares authorized; no shares issued and outstanding	-	-
Common stock, $0.01 par value; 120,000 shares authorized; 51,696 shares issued and 51,613 shares outstanding as of June 29, 2024, and 51,338 shares issued and outstanding as of December 30, 2023	517	513
Additional paid-in capital	1,956,629	1,905,578
Retained earnings	2,053,557	1,887,218
Treasury stock, at cost, 83 and zero shares, as of June 29, 2024 and December 30, 2023, respectively	(18,265)	-
Accumulated other comprehensive loss	(269,709)	(196,427)
Total Charles River Laboratories International, Inc. equity	3,722,729	3,596,882
Nonredeemable noncontrolling interests	4,289	5,394
Total equity	3,727,018	3,602,276
Total liabilities, equity and noncontrolling interests	$	7,948,283	$	8,195,001

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SCHEDULE 3
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
(in thousands)
Six Months Ended
June 29, 2024	July 1, 2023
Cash flows relating to operating activities
Net income	$	168,743	$	203,397
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation and amortization	171,439	154,740
Stock-based compensation	33,325	29,730
Deferred income taxes	(13,073)	(16,555)
Long-lived asset impairment charges	14,250	10,453
(Gain) loss on venture capital & strategic equity investments, net	(6,305)	5,176
Provision for credit losses	4,719	9,849
Loss on divestitures, net	659	563
Other, net	9,090	3,229
Changes in assets and liabilities:
Trade receivables and contract assets, net	1,072	(48,249)
Inventories	9,750	(32,671)
Accounts payable	(6,436)	(24,985)
Accrued compensation	(33,153)	(7,648)
Deferred revenue	8,151	(6,796)
Customer contract deposits	7,849	(17,519)
Other assets and liabilities, net	(46,657)	(5,209)
Net cash provided by operating activities	323,423	257,505
Cash flows relating to investing activities
Acquisition of businesses and assets, net of cash acquired	(5,479)	(50,166)
Capital expenditures	(118,630)	(174,258)
Purchases of investments and contributions to venture capital investments	(35,538)	(22,689)
Proceeds from sale of investments	12,359	2,943
Other, net	(370)	(1,057)
Net cash used in investing activities	(147,658)	(245,227)
Cash flows relating to financing activities
Proceeds from long-term debt and revolving credit facility	741,200	281,796
Proceeds from exercises of stock options	22,331	15,719
Payments on long-term debt, revolving credit facility, and finance lease obligations	(987,344)	(317,049)
Purchase of treasury stock	(18,265)	(23,978)
Payments of contingent consideration	-	(2,711)
Purchases of additional equity interests, net	(12,000)	-
Other, net	(13,434)	-
Net cash provided by financing activities	(267,512)	(46,223)
Effect of exchange rate changes on cash, cash equivalents, and restricted cash	(11,729)	1,508
Net change in cash, cash equivalents, and restricted cash	(103,476)	(32,437)
Cash, cash equivalents, and restricted cash, beginning of period	284,480	241,214
Cash, cash equivalents, and restricted cash, end of period	$	181,004	$	208,777

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SCHEDULE 4
RECONCILIATION OF GAAP TO NON-GAAP
SELECTED BUSINESS SEGMENT INFORMATION (UNAUDITED)(1)
(in thousands, except percentages)
Three Months Ended	Six Months Ended
June 29, 2024	July 1, 2023	June 29, 2024	July 1, 2023
Research Models and Services
Revenue	$	206,389	$	209,948	$	427,296	$	409,714
Operating income	29,948	48,918	73,097	89,327
Operating income as a % of revenue	14.5	%	23.3	%	17.1	%	21.8	%
Add back:
Amortization related to acquisitions	7,357	5,491	17,645	10,985
Acquisition related adjustments (2)	174	997	337	1,827
Severance	494	-	1,034	-
Site consolidation and impairment charges	9,728	-	16,574	-
Total non-GAAP adjustments to operating income	$	17,753	$	6,488	$	35,590	$	12,812
Operating income, excluding non-GAAP adjustments	$	47,701	$	55,406	$	108,687	$	102,139
Non-GAAP operating income as a % of revenue	23.1	%	26.4	%	25.4	%	24.9	%
Depreciation and amortization	$	16,538	$	13,949	$	34,661	$	27,438
Capital expenditures	$	9,313	$	7,493	$	29,357	$	26,577
Discovery and Safety Assessment
Revenue	$	627,419	$	663,457	$	1,232,871	$	1,325,810
Operating income	138,376	161,538	253,215	332,969
Operating income as a % of revenue	22.1	%	24.3	%	20.5	%	25.1	%
Add back:
Amortization related to acquisitions	20,298	17,744	38,894	35,231
Acquisition related adjustments (2)	5,591	2,359	5,783	2,603
Severance	2,429	-	7,913	-
Site consolidation and impairment charges	1,337	-	2,344	-
Third-party legal costs (3)	2,110	1,492	4,301	4,297
Total non-GAAP adjustments to operating income	$	31,765	$	21,595	$	59,235	$	42,131
Operating income, excluding non-GAAP adjustments	$	170,141	$	183,133	$	312,450	$	375,100
Non-GAAP operating income as a % of revenue	27.1	%	27.6	%	25.3	%	28.3	%
Depreciation and amortization	$	47,729	$	43,124	$	93,518	$	85,574
Capital expenditures	$	19,444	$	48,326	$	68,403	$	113,510
Manufacturing Solutions
Revenue	$	192,309	$	186,532	$	377,510	$	353,786
Operating income	37,230	24,403	70,911	26,509
Operating income as a % of revenue	19.4	%	13.1	%	18.8	%	7.5	%
Add back:
Amortization related to acquisitions	10,768	11,125	21,561	23,146
Acquisition related adjustments (2)	544	2,182	1,243	3,011
Severance	1,671	2,517	3,194	3,433
Site consolidation and impairment charges	990	182	1,090	2,754
Third-party legal costs (3)	-	2,368	-	6,858
Total non-GAAP adjustments to operating income	$	13,973	$	18,374	$	27,088	$	39,202
Operating income, excluding non-GAAP adjustments	$	51,203	$	42,777	$	97,999	$	65,711
Non-GAAP operating income as a % of revenue	26.6	%	22.9	%	26.0	%	18.6	%
Depreciation and amortization	$	20,073	$	19,523	$	39,878	$	39,607
Capital expenditures	$	10,583	$	10,862	$	19,445	$	32,600
Unallocated Corporate Overhead	$	(53,902)	$	(69,914)	$	(119,594)	$	(115,968)
Add back:
Acquisition related adjustments (2)	2,108	4,799	3,637	7,002
Severance	1,304	-	2,794	-
Total non-GAAP adjustments to operating expense	$	3,412	$	4,799	$	6,431	$	7,002
Unallocated corporate overhead, excluding non-GAAP adjustments	$	(50,490)	$	(65,115)	$	(113,163)	$	(108,966)
Total
Revenue	$	1,026,117	$	1,059,937	$	2,037,677	$	2,089,310
Operating income	151,652	164,945	277,629	332,837
Operating income as a % of revenue	14.8	%	15.6	%	13.6	%	15.9	%
Add back:
Amortization related to acquisitions	38,423	34,360	78,100	69,362
Acquisition related adjustments (2)	8,417	10,337	11,000	14,443
Severance	5,898	2,517	14,935	3,433
Site consolidation and impairment charges	12,055	182	20,008	2,754
Third-party legal costs (3)	2,110	3,860	4,301	11,155
Total non-GAAP adjustments to operating income	$	66,903	$	51,256	$	128,344	$	101,147
Operating income, excluding non-GAAP adjustments	$	218,555	$	216,201	$	405,973	$	433,984
Non-GAAP operating income as a % of revenue	21.3	%	20.4	%	19.9	%	20.8	%
Depreciation and amortization	$	86,082	$	77,671	$	171,439	$	154,740
Capital expenditures	$	39,486	$	67,383	$	118,630	$	174,258
(1)	Charles River management believes that supplementary non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of often-one-time charges and other items which are outside our normal operations, consistent with the manner in which management measures and forecasts the Company's performance. The supplementary non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with U.S. GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules, regulations and guidance.
(2)	These adjustments are related to the evaluation and integration of acquisitions, which primarily include transaction, third-party integration, and certain compensation costs, and fair value adjustments associated with contingent consideration arrangements.
(3)	Third-party legal costs are related to (a) an environmental litigation related to the Microbial Solutions business and (b) investigations by the U.S. government into the NHP supply chain applicable to our Safety Assessment business.

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SCHEDULE 5
RECONCILIATION OF GAAP EARNINGS TO NON-GAAP EARNINGS (UNAUDITED)(1)
(in thousands, except per share data)
Three Months Ended	Six Months Ended
June 29, 2024	July 1, 2023	June 29, 2024	July 1, 2023
Net income available to Charles River Laboratories International, Inc. common shareholders	$	89,988	$	97,020	$	157,317	$	200,151
Add back:
Adjustment of redeemable noncontrolling interest (2)	301	-	702	-
Incremental dividends attributable to noncontrolling interest holders (3)	3,792	-	9,022	-
Non-GAAP adjustments to operating income (4)	65,576	51,256	127,017	101,147
Venture capital and strategic equity investment (gains) losses, net	(902)	1,873	(6,664)	5,155
(Gain) loss on divestitures (5)	-	1,003	658	562
Other (6)	-	596	-	495
Tax effect of non-GAAP adjustments:
Non-cash tax provision related to international financing structure (7)	871	1,296	1,212	2,420
Tax effect of the remaining non-GAAP adjustments	(14,687)	(14,759)	(26,715)	(28,658)
Net income attributable to Charles River Laboratories International, Inc. common shareholders, excluding non-GAAP adjustments	$	144,939	$	138,285	$	262,549	$	281,272
Weighted average shares outstanding - Basic	51,551	51,216	51,494	51,157
Effect of dilutive securities:
Stock options, restricted stock units and performance share units	295	251	316	225
Weighted average shares outstanding - Diluted	51,846	51,467	51,810	51,382
Earnings per share attributable to common shareholders:
Basic	$	1.75	$	1.89	$	3.06	$	3.91
Diluted	$	1.74	$	1.89	$	3.04	$	3.90
Basic, excluding non-GAAP adjustments	$	2.81	$	2.70	$	5.10	$	5.50
Diluted, excluding non-GAAP adjustments	$	2.80	$	2.69	$	5.07	$	5.47
(1)	Charles River management believes that supplementary non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of often-one-time charges and other items which are outside our normal operations, consistent with the manner in which management measures and forecasts the Company's performance. The supplementary non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with U.S. GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules, regulations and guidance.
(2)	This amount represents accretion adjustments of the Noveprim redeemable noncontrolling interest.
(3)	This amount represents incremental undeclared dividends attributable to Noveprim noncontrolling interest holders who receive preferential dividends for fiscal year 2024.
(4)	This amount excludes Non-GAAP adjustments attributable to noncontrolling interest holders.
(5)	The amount included in 2024 relates to a loss on the sale of a Safety Assessment site. Adjustments included in 2023 relate to the gain on the sale of our Avian Vaccine business, which was divested in 2022.
(6)	Amounts included in 2023 relate to a final adjustment on the termination of a Canadian pension plan.
(7)	This amount relates to the recognition of deferred tax assets expected to be utilized as a result of changes to the Company's international financing structure.

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
SCHEDULE 6
RECONCILIATION OF GAAP REVENUE GROWTH
TO NON-GAAP REVENUE GROWTH, ORGANIC (UNAUDITED) (1)
Three Months Ended June 29, 2024	Total CRL	RMS Segment	DSA Segment	MS Segment
Revenue growth, reported	(3.2)	%	(1.7)	%	(5.4)	%	3.1	%
(Increase) decrease due to foreign exchange	0.3	%	0.5	%	0.1	%	0.6	%
Contribution from acquisitions (2)	(0.5)	%	(2.7)	%	-	%	-	%
Impact of divestitures (3)	0.2	%	-	%	0.3	%	-	%
Non-GAAP revenue growth, organic (4)	(3.2)	%	(3.9)	%	(5.0)	%	3.7	%
Six Months Ended June 29, 2024	Total CRL	RMS Segment	DSA Segment	MS Segment
Revenue growth, reported	(2.5)	%	4.3	%	(7.0)	%	6.7	%
(Increase) decrease due to foreign exchange	-	%	0.4	%	(0.3)	%	0.2	%
Contribution from acquisitions (2)	(1.0)	%	(5.1)	%	-	%	-	%
Impact of divestitures (3)	0.3	%	-	%	0.4	%	-	%
Non-GAAP revenue growth, organic (4)	(3.2)	%	(0.4)	%	(6.9)	%	6.9	%
(1)	Charles River management believes that supplementary non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of often-one-time charges and other items which are outside our normal operations, consistent with the manner in which management measures and forecasts the Company's performance. The supplementary non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with U.S. GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules, regulations and guidance.
(2)	The contribution from acquisitions reflects only completed acquisitions.
(3)	Impact of divestitures relates to the sale of a site within our Safety Assessment business.
(4)	Organic revenue growth is defined as reported revenue growth adjusted for acquisitions, divestitures, and foreign exchange.