Management Change/Compensation Form 8 K

Item 5.02.   Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On November 27, 2024, David Lemus notified the Board of Directors (the "Board") of Scilex Holding Company (the "Company") that he was resigning from the Board, all committees of the Board and any director or officer position held with any subsidiary of the Company, effective as of November 27, 2024, for personal and professional reasons. A copy of Mr. Lemus's resignation letter is attached hereto as Exhibit 17.1 and is incorporated herein by reference.