Statement of Changes in Beneficial Ownership - Form 4

Ownership Submission

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Kelderman Kim 2. Issuer Name and Ticker or Trading Symbol BIO-TECHNE Corp [TECH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) 614 MCKINLEY PLACE NE 3. Date of Earliest Transaction (Month/Day/Year) 11/01/2024 (Street) MINNEAPOLIS, MN 55413 4. If Amendment, Date Original Filed (Month/Day/Year) 6. Individual or Joint/Group Filing (Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 11/01/2024 F 2,430 D $75.31 39,004 D

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)	5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)	6. Date Exercisable and Expiration Date (Month/Day/Year)	7. Title and Amount of Underlying Securities (Instr. 3 and 4)	8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$37.7							(1)	05/01/2025	Common Stock	13,392		13,392	D
Stock Option (Right to Buy)	$44.33							(1)	08/08/2025	Common Stock	84,308		84,308	D
Stock Option (Right to Buy)	$47.6							(1)	08/07/2026	Common Stock	109,536		109,536	D
Stock Option (Right to Buy)	$66.97							(1)	08/05/2027	Common Stock	115,724		115,724	D
Stock Option (Right to Buy)	$120.46							(2)	08/06/2028	Common Stock	25,944		25,944	D
Performance Restricted Stock Units	(3)							(4)	(4)	Common Stock	6,984		6,984	D
Performance Stock Options (Right to Buy)	$94.52							(4)	08/15/2029	Common Stock	21,704		21,704	D
Stock Options (Right to Buy)	$94.52							(5)	08/15/2029	Common Stock	28,940		28,940	D
Performance Restricted Stock Units	(3)							(6)	(6)	Common Stock	8,873		8,873	D
Performance Stock Options (Right to Buy)	$84.61							(6)	08/15/2030	Common Stock	23,881		23,881	D
Stock Options (Right to Buy)	$84.61							(7)	08/15/2030	Common Stock	29,391		29,391	D
Stock Options (Right to Buy)	$52.83							(8)	11/01/2030	Common Stock	38,252		38,252	D
Performance Restricted Stock Units	(3)							(6)	(6)	Common Stock	9,423		9,423	D
Performance Stock Options (Right to Buy)	$68.54							(6)	02/01/2031	Common Stock	25,945		25,945	D
Stock Options (Right to Buy)	$68.54							(9)	02/01/2031	Common Stock	51,890		51,890	D
Performance Restricted Stock Units	(3)							(10)	(10)	Common Stock	51,261		51,261	D
Restricted Stock Units	(3)							(11)	(11)	Common Stock	25,630		25,630	D
Stock Options (Right to Buy)	$74.91							(12)	08/15/2034	Common Stock	69,061		69,061	D

Reporting Owners

Reporting Owner Name / Address	Relationships
Director	10% Owner	Officer	Other
Kelderman Kim 614 MCKINLEY PLACE NE MINNEAPOLIS, MN 55413	X		Chief Executive Officer

Signatures

/s/ Andrew Nick, Attorney-in-Fact for Kim Kelderman pursuant to Power of Attorney previously filed.	11/05/2024
**Signature of Reporting Person	Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Fully exercisable.
(2)	Options to purchase 6,484 shares vest on each of 8/6/2022 and 8/6/2023 and options to purchase 6,488 shares vest on each of 8/6/2024 and 8/6/2025.
(3)	Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock.
(4)	Vests in full or in part on 8/15/2025 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(5)	Options to purchase 7,236 shares vest on each of 8/15/2023, 8/15/2024 and 8/15/2026 and options to purchase 7,232 shares vest on 8/15/2025.
(6)	Vests in full or in part on 8/15/2026 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(7)	Options to purchase 7,348 shares vest on each of 8/15/2024, 8/15/2025 and 8/15/2027 and options to purchase 7,347 shares vest on 8/15/2026.
(8)	Options to purchase 9,563 shares vest on each of 11/1/2024, 11/1/2025, 11/1/2026 and 11/1/2027.
(9)	Options to purchase 12,973 shares vest on each of 2/1/2025 and 2/1/2027, and options to purchase 12,972 shares vest on each of 2/1/2026 and 2/1/2028.
(10)	Vests in full or in part on 8/15/2027 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(11)	8,543 restricted stock units vest on each of 8/15/2025 and 8/15/2026, and 8,544 restricted stock units vest on 8/15/2027.
(12)	Options to purchase 17,265 shares vest on each of 8/15/2025, 8/15/2026 and 8/15/2027, and options to purchase 17,266 shares vest on 8/15/2028.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure. Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.

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